Joel Hedlund (NSC) at 09:28, 4 June 2012

2012-06-04T09:28:23Z

Joel Hedlund (NSC): Created page with "Category:Bioinformatics The purpose of [http://en.wikipedia.org/wiki/Multiple_sequence_alignment multiple sequence alignment] is to match up a number of related biological se..."

2012-06-04T09:23:04Z

Created page with "Category:Bioinformatics The purpose of [http://en.wikipedia.org/wiki/Multiple_sequence_alignment multiple sequence alignment] is to match up a number of related biological se..."

New page

[[Category:Bioinformatics]]
The purpose of [http://en.wikipedia.org/wiki/Multiple_sequence_alignment multiple sequence alignment] is to match up a number of related biological sequences against one another as well as possible, so that in each position in the resulting alignment, all residues have the same biological role in the original sequences. This is done by moving and stretching the sequences with respect to one another, eventually finding the optimal fit. This is essentially a multidimensional optimisation problem with a large solution space, so clever heuristics are needed in order to make the problem tractable. Many algorithms have been proposed for solving this with maximal efficiency, and there is often a tradeoff between quality on one hand, and speed and slim resource requirements on the other.

← Older revision		Revision as of 09:28, 4 June 2012
Line 1:		Line 1:
	[[Category:Bioinformatics]]		[[Category:Bioinformatics]]
	The purpose of [http://en.wikipedia.org/wiki/Multiple_sequence_alignment multiple sequence alignment] is to match up a number of related biological sequences against one another as well as possible, so that in each position in the resulting alignment, all residues have the same biological role in the original sequences. This is done by moving and stretching the sequences with respect to one another, eventually finding the optimal fit. This is essentially a multidimensional optimisation problem with a large solution space, so clever heuristics are needed in order to make the problem tractable. Many algorithms have been proposed for solving this with maximal efficiency, and there is often a tradeoff between quality on one hand, and speed and slim resource requirements on the other.		The purpose of [http://en.wikipedia.org/wiki/Multiple_sequence_alignment multiple sequence alignment] is to match up a number of related biological sequences against one another as well as possible, so that in each position in the resulting alignment, all residues have the same biological role in the original sequences. This is done by moving and stretching the sequences with respect to one another, eventually finding the optimal fit. This is essentially a multidimensional optimisation problem with a large solution space, so clever heuristics are needed in order to make the problem tractable. Many algorithms have been proposed for solving this with maximal efficiency, and there is often a tradeoff between quality on one hand, and speed and slim resource requirements on the other.
		+
		+	== Experts ==
		+	{{list experts}}

Category:Multiple sequence alignment - Revision history

Joel Hedlund (NSC) at 09:28, 4 June 2012

Joel Hedlund (NSC): Created page with "Category:Bioinformatics The purpose of [http://en.wikipedia.org/wiki/Multiple_sequence_alignment multiple sequence alignment] is to match up a number of related biological se..."